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Issue 16, 2017
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Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

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Abstract

Halloysite (HNT) is a promising natural nanosized tubular clay mineral that has many important uses in different industrial fields. It is naturally occurring, biocompatible, and available in thousands of tons at low cost. As a consequence of a hollow cavity, HNT is mainly used as nanocontainer for the controlled release of several chemicals. Chemical modification of both surfaces (inner lumen and outer surface) is a strategy to tune the nanotube's properties. Specifically, chemical modification of HNT surfaces generates a nanoarchitecture with targeted affinity through outer surface functionalization and drug transport ability from functionalization of the nanotube lumen. The primary focus of this review is the research of modified halloysite nanotubes and their applications in biological and medical fields.

Graphical abstract: Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

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Publication details

The article was received on 30 Jan 2017, accepted on 08 Mar 2017 and first published on 09 Mar 2017


Article type: Review Article
DOI: 10.1039/C7TB00316A
Citation: J. Mater. Chem. B, 2017,5, 2867-2882
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    Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

    M. Massaro, G. Lazzara, S. Milioto, R. Noto and S. Riela, J. Mater. Chem. B, 2017, 5, 2867
    DOI: 10.1039/C7TB00316A

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