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Issue 19, 2017
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Highly selective organic transistor biosensor with inkjet printed graphene oxide support system

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Abstract

Most of the reported field effect transistors (FETs) fall short of a general method to uniquely specify and detect a target analyte. For this reason, we propose a pentacene-based FET with a graphene oxide support system (GOSS), composed of functionalized graphene oxide (GO) ink. The GOSS with a specific moiety group to capture the biomaterial of interest was inkjet printed on the pentacene FET. It provided modular receptor sites on the surface of pentacene, without alteration of the device. To evaluate the performance of a GOSS-pentacene FET biosensor, we detected the artificial DNA and circulating tumor cells as a proof-of-concept. The mobility of the FET dramatically changed upon capturing the target biomolecule on the GOSS. The FET exhibited high selectivity with 0.1 pmoles of the target DNA and a few cancer cells per detection volume. This study suggests a valuable sensor for medical diagnosis that can be mass produced effortlessly at low-cost.

Graphical abstract: Highly selective organic transistor biosensor with inkjet printed graphene oxide support system

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Publication details

The article was received on 26 Dec 2016, accepted on 27 Mar 2017 and first published on 28 Mar 2017


Article type: Paper
DOI: 10.1039/C6TB03357A
Citation: J. Mater. Chem. B, 2017,5, 3580-3585
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    Highly selective organic transistor biosensor with inkjet printed graphene oxide support system

    D. Lee, H. Cho, D. Han, R. Chand, T. Yoon and Y. Kim, J. Mater. Chem. B, 2017, 5, 3580
    DOI: 10.1039/C6TB03357A

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