Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 13, 2017
Previous Article Next Article

Versatile graphene-based photothermal nanocomposites for effectively capturing and killing bacteria, and for destroying bacterial biofilms

Author affiliations

Abstract

Bacterial infection is a worldwide health problem. Finding new potential antibacterial materials and developing advanced treatment strategies are becoming increasingly important and urgent. Herein, a versatile graphene-based photothermal nanocomposite was prepared for rapidly capturing and effectively eliminating both Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli), and for destroying bacterial biofilms with near-infrared (NIR) irradiation. In this work, chitosan-functionalized magnetic graphene oxide (GO–IO–CS) was synthesized as a multifunctional therapy agent through a hydrothermal method. Chitosan could efficiently contact and capture bacteria by its positively charged surface functional groups, and graphene oxide could act as an effective photothermal killer to convert NIR light into local heat to enhance antibacterial activity. The super-paramagnetic properties of GO–IO–CS made it easy to separate and aggregate the bacteria, so improving the photothermal sterilization efficiency. GO–IO–CS was demonstrated to eliminate bacteria effectively after 10 min of NIR irradiation and to destroy bacterial biofilms. Furthermore, this antibiotic agent could be regenerated with an external magnet and reused in a subsequent antibacterial application.

Graphical abstract: Versatile graphene-based photothermal nanocomposites for effectively capturing and killing bacteria, and for destroying bacterial biofilms

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 28 Nov 2016, accepted on 02 Mar 2017 and first published on 15 Mar 2017


Article type: Paper
DOI: 10.1039/C6TB03084J
Citation: J. Mater. Chem. B, 2017,5, 2459-2467
  •   Request permissions

    Versatile graphene-based photothermal nanocomposites for effectively capturing and killing bacteria, and for destroying bacterial biofilms

    X. Jia, I. Ahmad, R. Yang and C. Wang, J. Mater. Chem. B, 2017, 5, 2459
    DOI: 10.1039/C6TB03084J

Search articles by author