Jump to main content
Jump to site search


Stretching of surface-tethered polymers in pressure-driven flow under confinement

Author affiliations

Abstract

We study the effect of pressure-driven flow on a single surface-tethered DNA molecule confined between parallel surfaces. The influence of flow and channel parameters as well as the length of the molecules on their extension and orientation is explored. In the experiments the chain conformations are imaged by laser scanning confocal microscopy. We find that the fractional extension of the tethered DNA molecules mainly depends on the wall shear stress, with effects of confinement being very weak. Experiments performed with molecules of different contour length show that the fractional extension is a universal function of the product of the wall shear stress and the contour length, a result that can be obtained from a simple scaling relation. The experimental results are in good agreement with results from coarse-grained molecular dynamics/Lattice-Boltzmann simulations.

Graphical abstract: Stretching of surface-tethered polymers in pressure-driven flow under confinement

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Feb 2017, accepted on 20 Jul 2017 and first published on 24 Jul 2017


Article type: Paper
DOI: 10.1039/C7SM00306D
Citation: Soft Matter, 2017, Advance Article
  •   Request permissions

    Stretching of surface-tethered polymers in pressure-driven flow under confinement

    T. Roy, K. Szuttor, J. Smiatek, C. Holm and S. Hardt, Soft Matter, 2017, Advance Article , DOI: 10.1039/C7SM00306D

Search articles by author

Spotlight

Advertisements