Jump to main content
Jump to site search

Issue 9, 2017
Previous Article Next Article

Photochromic coenzyme Q derivatives: switching redox potentials with light

Author affiliations

Abstract

Coenzyme Q is an important redox cofactor involved in a variety of cellular processes, and is thus found in several cell compartments. We report a photochromic derivative of coenzyme Q that combines the molecular structures of the redox active cofactor and a photochromic dye. Light irradiation triggers an electronic rearrangement reversibly changing the redox potential. We used this effect to control the intermolecular redox reaction of the photochromic coenzyme Q derivative with dihydropyridine in solution by light irradiation. On mitochondria, the altered redox properties showed an effect on the respiratory chain. The experiments demonstrate that the redox reactions can be initiated inside the system of interest through irradiation with light and the accompanied photoisomerization.

Graphical abstract: Photochromic coenzyme Q derivatives: switching redox potentials with light

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Feb 2017, accepted on 19 Jul 2017 and first published on 20 Jul 2017


Article type: Edge Article
DOI: 10.1039/C7SC00781G
Citation: Chem. Sci., 2017,8, 6474-6483
  • Open access: Creative Commons BY license
  •   Request permissions

    Photochromic coenzyme Q derivatives: switching redox potentials with light

    N. A. Simeth, A. C. Kneuttinger, R. Sterner and B. König, Chem. Sci., 2017, 8, 6474
    DOI: 10.1039/C7SC00781G

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements