Jump to main content
Jump to site search

Issue 4, 2017
Previous Article Next Article

A mild catalytic system for radical conjugate addition of nitrogen heterocycles

Author affiliations

Abstract

The direct addition of pyridine and diazine units to electron-poor alkenes has been achieved via a redox radical mechanism that is enabled by limiting the effective concentration of the hydrogen-atom source. The described method is tolerant of acidic functional groups and is generally applicable to the union of a wide range of Michael acceptors and 6-membered heterocyclic halides.

Graphical abstract: A mild catalytic system for radical conjugate addition of nitrogen heterocycles

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jan 2017, accepted on 13 Feb 2017 and first published on 13 Feb 2017


Article type: Edge Article
DOI: 10.1039/C7SC00243B
Citation: Chem. Sci., 2017,8, 3121-3125
  • Open access: Creative Commons BY license
  •   Request permissions

    A mild catalytic system for radical conjugate addition of nitrogen heterocycles

    R. A. Aycock, H. Wang and N. T. Jui, Chem. Sci., 2017, 8, 3121
    DOI: 10.1039/C7SC00243B

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements