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Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

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Abstract

The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive ‘molecular rotors’ to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.

Graphical abstract: Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

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Publication details

The article was received on 07 Dec 2016, accepted on 14 Feb 2017, published on 14 Feb 2017 and first published online on 14 Feb 2017


Article type: Edge Article
DOI: 10.1039/C6SC05369F
Citation: Chem. Sci., 2017, Advance Article
  • Open access: Creative Commons BY-NC license
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    Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

    P. S. Sherin, I. López-Duarte, M. R. Dent, M. Kubánková, A. Vyšniauskas, J. A. Bull, E. S. Reshetnikova, A. S. Klymchenko, Y. P. Tsentalovich and M. K. Kuimova, Chem. Sci., 2017, Advance Article , DOI: 10.1039/C6SC05369F

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