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Issue 2, 2017
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How molecular motors work – insights from the molecular machinist's toolbox: the Nobel prize in Chemistry 2016

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Abstract

The Nobel prize in Chemistry for 2016 was awarded to Jean Pierre Sauvage, Sir James Fraser Stoddart, and Bernard (Ben) Feringa for their contributions to the design and synthesis of molecular machines. While this field is still in its infancy, and at present there are no commercial applications, many observers have stressed the tremendous potential of molecular machines to revolutionize technology. However, perhaps the most important result so far accruing from the synthesis of molecular machines is the insight provided into the fundamental mechanisms by which molecular motors, including biological motors such as kinesin, myosin, FoF1 ATPase, and the flagellar motor, function. The ability to “tinker” with separate components of molecular motors allows asking, and answering, specific questions about mechanism, particularly with regard to light driven vs. chemistry driven molecular motors.

Graphical abstract: How molecular motors work – insights from the molecular machinist's toolbox: the Nobel prize in Chemistry 2016

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Publication details

The article was received on 29 Oct 2016, accepted on 18 Nov 2016 and first published on 21 Nov 2016


Article type: Minireview
DOI: 10.1039/C6SC04806D
Citation: Chem. Sci., 2017,8, 840-845
  • Open access: Creative Commons BY license
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    How molecular motors work – insights from the molecular machinist's toolbox: the Nobel prize in Chemistry 2016

    R. D. Astumian, Chem. Sci., 2017, 8, 840
    DOI: 10.1039/C6SC04806D

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