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Issue 40, 2017, Issue in Progress
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Novel Fe3O4@GNF@SiO2 nanocapsules fabricated through the combination of an in situ formation method and SiO2 coating process for magnetic resonance imaging

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Abstract

An in situ approach for the synthesis of Fe3O4 nanoparticles combined with a SiO2 coating process was employed to prepare Fe3O4@GNF@SiO2 nanocapsules. Graphitised nanofibres (GNF) were initially filled with iron(III) acetylacetonate, and used as a precursor for the synthesis of ultrasmall Fe3O4 nanoparticles (4.6 nm in diameter) inside the cavities of GNF (Fe3O4@GNF) with a high density. By using a silica coating process, Fe3O4@GNF@SiO2 nanocapsules were obtained. The presence of the silica shell not only prevented leakage of the nanoparticles from inside the GNF but also protected the magnetite nanoparticles from dissolution, even in harsh acidic conditions. Furthermore, the silica coating resulted in an increased dispersability of the nanocomposites in water. Magnetic resonance imaging (MRI) studies indicate relatively high Image ID:c7ra04080f-t1.gif relaxivities for Fe3O4@GNF nanocomposites and Fe3O4@GNF@SiO2 nanocapsules revealing the potential application of these hybrid materials for bioimaging. Therefore, the coating of filled GNF with silica is as an excellent strategy for the protection of encapsulated payloads.

Graphical abstract: Novel Fe3O4@GNF@SiO2 nanocapsules fabricated through the combination of an in situ formation method and SiO2 coating process for magnetic resonance imaging

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Publication details

The article was received on 10 Apr 2017, accepted on 28 Apr 2017 and first published on 08 May 2017


Article type: Paper
DOI: 10.1039/C7RA04080F
Citation: RSC Adv., 2017,7, 24690-24697
  • Open access: Creative Commons BY license
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    Novel Fe3O4@GNF@SiO2 nanocapsules fabricated through the combination of an in situ formation method and SiO2 coating process for magnetic resonance imaging

    C. Lu, S. Sandoval, T. Puig, X. Obradors, G. Tobias, J. Ros and S. Ricart, RSC Adv., 2017, 7, 24690
    DOI: 10.1039/C7RA04080F

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