Copper-catalyzed C–C direct cross-coupling: an efficient approach to phenyl-2-(phenylthiophenyl)-methanones†
Abstract
An efficient copper-catalyzed C–C bond direct cross-coupling reaction has been developed. Starting from diaryl sulfoxides and aromatic aldehydes, versatile phenyl-2-(phenylthiophenyl)-methanones were efficiently synthesized with high tolerance of functional groups under moderate conditions in water. This new methodology provides an economical and environmentally friendly approach toward C(sp2)–C(sp2) bond formation.

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