Jump to main content
Jump to site search


1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

Author affiliations

Abstract

A formal 1,6-conjugated addition-mediated [4 + 1] annulation of ortho-hydroxyphenyl-substituted para-quinone methides with sulfonium or ammonium bromides has been described. This domino-type process offered an efficient method for the synthesis of 2,3-dihydrobenzofurans in good yields, exhibiting good functional group tolerance, scalability and high diastereoselectivity.

Graphical abstract: 1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Sep 2017, accepted on 06 Nov 2017 and first published on 07 Nov 2017


Article type: Research Article
DOI: 10.1039/C7QO00846E
Citation: Org. Chem. Front., 2018, Advance Article
  •   Request permissions

    1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

    L. Liu, Z. Yuan, R. Pan, Y. Zeng, A. Lin, H. Yao and Y. Huang, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C7QO00846E

Search articles by author

Spotlight

Advertisements