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10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

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Abstract

This method reports on the preparation of the chiral oxazoline iminopyridine (OIP) ligand and its applications in the asymmetric hydroboration and hydrosilylation of 1,1-disubstituted alkenes. These reactions could be carried out on a scale of 10 grams.

Graphical abstract: 10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

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Publication details

The article was received on 09 Sep 2017, accepted on 19 Oct 2017 and first published on 20 Oct 2017


Article type: Method
DOI: 10.1039/C7QO00816C
Citation: Org. Chem. Front., 2017, Advance Article
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    10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

    J. Chen, T. Xi and Z. Lu, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C7QO00816C

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