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Copper-Catalysed Dehydrogenative α-C(sp3)−H Amination of Tetrahydroquinolines with O–benzoyl hydroxylamines

Abstract

A copper-catalysed dehydrogenative -C(sp3)−H amination of tetrahydroquinolines with O–benzoyl hydroxylamines has been demonstrated for the first time, which proceeds with the merits of operational simplicity, good functional tolerance, mild conditions, the use of O2 as the oxidant and no need for installation of directing groups.

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Publication details

The article was received on 04 Sep 2017, accepted on 11 Oct 2017 and first published on 12 Oct 2017


Article type: Research Article
DOI: 10.1039/C7QO00794A
Citation: Org. Chem. Front., 2017, Accepted Manuscript
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    Copper-Catalysed Dehydrogenative α-C(sp3)−H Amination of Tetrahydroquinolines with O–benzoyl hydroxylamines

    H. Zhao, X. Chen, H. Jiang and M. Zhang, Org. Chem. Front., 2017, Accepted Manuscript , DOI: 10.1039/C7QO00794A

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