Jump to main content
Jump to site search


B2(OH)4-mediated one-pot synthesis of tetrahydroquinoxalines from 2-amino(nitro)anilines and 1,2-dicarbonyl compounds in water

Author affiliations

Abstract

A practical one-pot synthesis of tetrahydroquinoxalines from readily available 2-amino(nitro)anilines and 1,2-dicarbonyl compounds mediated by diboronic acid with water as both a solvent and a hydrogen donor under metal-free conditions has been discovered. The deuterium labeling experiments with D2O were also performed to demonstrate that water acts as the hydrogen donor.

Graphical abstract: B2(OH)4-mediated one-pot synthesis of tetrahydroquinoxalines from 2-amino(nitro)anilines and 1,2-dicarbonyl compounds in water

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Jul 2017, accepted on 08 Aug 2017 and first published on 09 Aug 2017


Article type: Research Article
DOI: 10.1039/C7QO00604G
Citation: Org. Chem. Front., 2017, Advance Article
  •   Request permissions

    B2(OH)4-mediated one-pot synthesis of tetrahydroquinoxalines from 2-amino(nitro)anilines and 1,2-dicarbonyl compounds in water

    S. Liu, Y. Zhou, Y. Sui, H. Liu and H. Zhou, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C7QO00604G

Search articles by author

Spotlight

Advertisements