Jump to main content
Jump to site search


Disilanes as oxygen scavengers and surrogates of hydrosilanes suitable for selective reduction of nitroarenes, phosphine oxides and other valuable substrates

Author affiliations

Abstract

In this report, we demonstrate that the reaction of nitroarenes with hexamethyldisilane under various conditions affords a different range of compounds with excellent selectivity. In particular, the reaction of nitroarenes with hexamethyldisilane using a CsF/TBAB/toluene system provides suitable azo compounds, while in the presence of a CsF/TBAB/[Pd]/EtOH system hexamethyldisilane acts as a novel surrogate of gaseous trimethylsilane, thus, reducing nitroarenes to corresponding anilines. The synthetic value of the developed methodology was further extended by the reduction of a wide range of substrates including N-oxides, sulfoxides, phosphine oxides etc.

Graphical abstract: Disilanes as oxygen scavengers and surrogates of hydrosilanes suitable for selective reduction of nitroarenes, phosphine oxides and other valuable substrates

Back to tab navigation

Supplementary files

Publication details

The article was received on 08 Jul 2017, accepted on 04 Sep 2017 and first published on 05 Sep 2017


Article type: Research Article
DOI: 10.1039/C7QO00566K
Citation: Org. Chem. Front., 2017, Advance Article
  •   Request permissions

    Disilanes as oxygen scavengers and surrogates of hydrosilanes suitable for selective reduction of nitroarenes, phosphine oxides and other valuable substrates

    A. Gevorgyan, S. Mkrtchyan, T. Grigoryan and V. O. Iaroshenko, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C7QO00566K

Search articles by author

Spotlight

Advertisements