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Issue 11, 2017
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Pd-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups

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Abstract

The Pd(II)-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups, prevalent organic motifs found in vital biological and pharmaceutical molecules, has been achieved for the first time. The reactions proceed with high functional group tolerance in yields of 21–84%.

Graphical abstract: Pd-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups

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Publication details

The article was received on 29 Jun 2017, accepted on 03 Aug 2017 and first published on 04 Aug 2017


Article type: Research Article
DOI: 10.1039/C7QO00532F
Citation: Org. Chem. Front., 2017,4, 2167-2169
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    Pd-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups

    K. Tang, C. Wang, T. Gao, C. Pan and L. Sun, Org. Chem. Front., 2017, 4, 2167
    DOI: 10.1039/C7QO00532F

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