Jump to main content
Jump to site search

Issue 9, 2017
Previous Article Next Article

Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

Author affiliations

Abstract

A transition-metal-free intramolecular cross dehydrogenation coupling reaction of pyridinium was developed. The C(sp2)–H/C(sp2)–H coupling reaction involved an unprecedented intermolecular hydride transfer process from the 1,2-dihydropyridine intermediate to another molecule of pyridinium and formed 1,4-dihydropyridine. Unlike the well-known dehydrogenation coupling proceeded under oxidative conditions, this was the first example of the coupling reaction through a substrate self-promoted hydride transfer process.

Graphical abstract: Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 May 2017, accepted on 08 Jun 2017 and first published on 12 Jun 2017


Article type: Research Article
DOI: 10.1039/C7QO00389G
Citation: Org. Chem. Front., 2017,4, 1789-1793
  •   Request permissions

    Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

    W. Shang, S. Li, Y. Ding, Z. Pan, X. Tong and C. Xia, Org. Chem. Front., 2017, 4, 1789
    DOI: 10.1039/C7QO00389G

Search articles by author

Spotlight

Advertisements