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Photoinduced difunctionalization of 2,3-dihydrofuran for the efficient synthesis of 2,3-disubstituted tetrahydrofurans

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Abstract

A highly efficient photoinduced multicomponent difunctionalization of 2,3-dihydrofuran has been developed for the synthesis of 2,3-disubstituted tetrahydrofurans under mild reaction conditions. Compared to the previous procedures, the new regioselectivity of the olefin in 2,3-dihydrofuran is disclosed. Moreover, a wide range of functional groups were tolerated and the corresponding products were obtained in high yields.

Graphical abstract: Photoinduced difunctionalization of 2,3-dihydrofuran for the efficient synthesis of 2,3-disubstituted tetrahydrofurans

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Publication details

The article was received on 29 Mar 2017, accepted on 18 May 2017 and first published on 19 May 2017


Article type: Research Article
DOI: 10.1039/C7QO00242D
Citation: Org. Chem. Front., 2017, Advance Article
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    Photoinduced difunctionalization of 2,3-dihydrofuran for the efficient synthesis of 2,3-disubstituted tetrahydrofurans

    X. Zhu, M. Han, P. Li and L. Wang, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C7QO00242D

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