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Issue 8, 2017
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A new approach to arylhydrazides via the reaction of the Mitsunobu reagent with arynes: further application to access diverse nitrogen-containing heterocycles in one pot

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Abstract

A new route to arylhydrazides involving the reaction of two highly active intermediates, the 1,3-zwitterion generated in situ from the Mitsunobu reagent and arynes, under mild conditions has been developed. Further transformations of the versatile arylhydrazides to diverse nitrogen-containing heterocycles in one pot are also demonstrated.

Graphical abstract: A new approach to arylhydrazides via the reaction of the Mitsunobu reagent with arynes: further application to access diverse nitrogen-containing heterocycles in one pot

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Publication details

The article was received on 27 Mar 2017, accepted on 18 May 2017 and first published on 23 May 2017


Article type: Research Article
DOI: 10.1039/C7QO00238F
Citation: Org. Chem. Front., 2017,4, 1636-1639
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    A new approach to arylhydrazides via the reaction of the Mitsunobu reagent with arynes: further application to access diverse nitrogen-containing heterocycles in one pot

    B. Cheng, B. Bao, Y. Chen, N. Wang, Y. Li, R. Wang and H. Zhai, Org. Chem. Front., 2017, 4, 1636
    DOI: 10.1039/C7QO00238F

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