Issue 7, 2017
From the journal:

Organic Chemistry Frontiers

Organoiodine reagent-promoted intermolecular oxidative amination: synthesis of cyclopropyl spirooxindoles†

Zhiguo Zhang,*a   Yongchao Zhang,a   Guoqing Huangb  and  Guisheng Zhang*a  

* Corresponding authors

a Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China
E-mail: zhangzg@htu.edu.cn, zgs6668@yahoo.com

b Handan Purification Equipment Research Institute, Handan, Hebei 056027, P. R. China

Abstract

An efficient organoiodine-promoted intramolecular direct oxidative C(sp2)–N cross-coupling reaction was developed for the preparation of cyclopropyl spirooxindoles from readily available secondary cyclopropyl carboxamides.

Graphical abstract: Organoiodine reagent-promoted intermolecular oxidative amination: synthesis of cyclopropyl spirooxindoles

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Article information

DOI
https://doi.org/10.1039/C7QO00156H
Article type
Research Article
Submitted
27 Feb 2017
Accepted
17 Apr 2017
First published
18 Apr 2017

Org. Chem. Front., 2017,4, 1372-1375

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Organoiodine reagent-promoted intermolecular oxidative amination: synthesis of cyclopropyl spirooxindoles

Z. Zhang, Y. Zhang, G. Huang and G. Zhang, Org. Chem. Front., 2017, 4, 1372 DOI: 10.1039/C7QO00156H

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