Jump to main content
Jump to site search

Issue 7, 2017
Previous Article Next Article

Copper-catalyzed gem-difluoromethylenation of C(sp2)–H bonds of alkenes

Author affiliations

Abstract

Copper-catalyzed gem-difluoromethylenation of the C(sp2)–H bonds of alkenes with high functional group tolerance has been developed. This protocol is the first to efficiently achieve gem-difluoromethylenation of C(sp2)–H bonds of unactivated aliphatic terminal olefins and can be applied in a reaction cascade to achieve gem-difluoromethylenation/cyclization of alkenes.

Graphical abstract: Copper-catalyzed gem-difluoromethylenation of C(sp2)–H bonds of alkenes

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Feb 2017, accepted on 09 Mar 2017 and first published on 10 Mar 2017


Article type: Research Article
DOI: 10.1039/C7QO00119C
Citation: Org. Chem. Front., 2017,4, 1239-1243
  •   Request permissions

    Copper-catalyzed gem-difluoromethylenation of C(sp2)–H bonds of alkenes

    H. Xu, D. Wang, Y. Chen, W. Wan, H. Deng, K. Ma, S. Wu, J. Hao and H. Jiang, Org. Chem. Front., 2017, 4, 1239
    DOI: 10.1039/C7QO00119C

Search articles by author

Spotlight

Advertisements