Rhodium-catalyzed denitrogenative transannulation of 1,2,3-triazolyl-carbamates: efficient access to 4-aminooxazolidinones

Abstract

Herein we describe a novel Rh(II)-catalyzed intramolecular transannulation reaction of 1,2,3-triazolyl carbamates to access functionalized 4-aminooxazolidinones under operationally simple conditions with low catalyst loadings. A one-pot tandem Cu(I)-catalyzed synthesis of 1,2,3-triazolyl-carbamates from propargyl carbamates followed by their rearrangement/cyclization with Rh(II)-carboxylates was also presented.