Jump to main content
Jump to site search


Solvent-free ruthenium trichloride-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides: a convenient access to 2-aminopyridines

Author affiliations

Abstract

A convenient access to functionalized 2-aminopyridines via a solventless Ru-catalyzed [2 + 2 + 2] cycloaddition reaction of α,ω-diynes and cyanamides is described. This transformation efficiently proceeds in the presence of a stable, easy to handle, and cost-effective RuCl3·nH2O complex, leading to various 2-aminopyridines in good to excellent yields according to an eco-friendly, straightforward approach.

Graphical abstract: Solvent-free ruthenium trichloride-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides: a convenient access to 2-aminopyridines

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 20 Jan 2017, accepted on 09 Feb 2017 and first published on 09 Feb 2017


Article type: Research Article
DOI: 10.1039/C7QO00058H
Citation: Org. Chem. Front., 2017, Advance Article
  •   Request permissions

    Solvent-free ruthenium trichloride-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides: a convenient access to 2-aminopyridines

    F. Ye, M. Haddad, V. Michelet and V. Ratovelomanana-Vidal, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C7QO00058H

Search articles by author