Jump to main content
Jump to site search

Issue 6, 2017
Previous Article Next Article

Efficient synthesis of multiply substituted butenolides from keto acids and terminal alkynes promoted by combined acids

Author affiliations

Abstract

A general, efficient, and operationally simple approach to highly substituted butenolides through the annulation of keto acids and terminal alkynes is described. This reaction is promoted by the combination of Lewis and Brønsted acids, furnishing a variety of butenolides in synthetically useful yields.

Graphical abstract: Efficient synthesis of multiply substituted butenolides from keto acids and terminal alkynes promoted by combined acids

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Dec 2016, accepted on 13 Feb 2017 and first published on 14 Feb 2017


Article type: Research Article
DOI: 10.1039/C6QO00820H
Citation: Org. Chem. Front., 2017,4, 1029-1033
  •   Request permissions

    Efficient synthesis of multiply substituted butenolides from keto acids and terminal alkynes promoted by combined acids

    W. Mao and C. Zhu, Org. Chem. Front., 2017, 4, 1029
    DOI: 10.1039/C6QO00820H

Search articles by author

Spotlight

Advertisements