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Synthesis of fully-substituted 1,2,3-triazoles via copper(I)-catalyzed three-component coupling of sulfoximines, alkynes and azides

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Abstract

A copper(I)-catalyzed three-component reaction of sulfoximines, alkynes and azides is described. This reaction proceeds under mild conditions with copper salt as a catalyst and atmospheric oxygen as an oxidant to afford a variety of 1,2,3-triazolyl-5-sulfoximines in moderate to good yields.

Graphical abstract: Synthesis of fully-substituted 1,2,3-triazoles via copper(i)-catalyzed three-component coupling of sulfoximines, alkynes and azides

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Publication details

The article was received on 23 Nov 2016, accepted on 07 Feb 2017 and first published on 09 Feb 2017


Article type: Research Article
DOI: 10.1039/C6QO00725B
Citation: Org. Chem. Front., 2017, Advance Article
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    Synthesis of fully-substituted 1,2,3-triazoles via copper(I)-catalyzed three-component coupling of sulfoximines, alkynes and azides

    J. Xu and Q. Song, Org. Chem. Front., 2017, Advance Article , DOI: 10.1039/C6QO00725B

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