Jump to main content
Jump to site search

Issue 1, 2017
Previous Article Next Article

Thiophene-derived polymer dots for imaging endocytic compartments in live cells and broad-spectrum bacterial killing

Author affiliations

Abstract

In this work, we present a new type of polymer dot synthesized from bithiophene (pTh-Pdot) via a simple and high yield procedure. Owing to their high brightness, excellent photo-stability, good biocompatibility, and molecular size, pTh-Pdots are promising for bioimaging applications. As a proof-of-concept demonstration, pTh-Pdots are herein employed to track the endocytic pathway in live cells. Furthermore, we show that these polymeric nanoparticles can serve as potent antibacterial agents by making use of their ability to disrupt bacterial membranes and high peroxidase mimicking activity.

Graphical abstract: Thiophene-derived polymer dots for imaging endocytic compartments in live cells and broad-spectrum bacterial killing

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 May 2016, accepted on 29 Jun 2016 and first published on 29 Jul 2016


Article type: Research Article
DOI: 10.1039/C6QM00065G
Citation: Mater. Chem. Front., 2017,1, 152-157
  • Open access: Creative Commons BY license
  •   Request permissions

    Thiophene-derived polymer dots for imaging endocytic compartments in live cells and broad-spectrum bacterial killing

    K. P. Prasad, A. Than, N. Li, M. Alam SK, H. Duan, K. Pu, X. Zheng and P. Chen, Mater. Chem. Front., 2017, 1, 152
    DOI: 10.1039/C6QM00065G

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements