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AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

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Abstract

A series of new conjugated polyelectrolytes (CPEs) containing tetraphenylethene units are synthesized and characterized. They show apparent aggregation-induced emission (AIE) characteristics and give fluorescence covering from cyan to red with high emission efficiencies in aggregates. These AIE CPEs can directly enter and stain living cells for fluorescence imaging with low cytotoxicity, and can provide information on cellular viscosity at different locations based on fluorescence lifetime imaging.

Graphical abstract: AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

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Publication details

The article was received on 04 Apr 2017, accepted on 01 Jun 2017 and first published on 05 Jun 2017


Article type: Communication
DOI: 10.1039/C7PY00564D
Citation: Polym. Chem., 2017, Advance Article
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    AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

    M. Gao, Y. Hong, B. Chen, Y. Wang, W. Zhou, W. W. H. Wong, J. Zhou, T. A. Smith and Z. Zhao, Polym. Chem., 2017, Advance Article , DOI: 10.1039/C7PY00564D

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