Jump to main content
Jump to site search


Fingerprinting antibiotics with PAE-based fluorescent sensor arrays

Author affiliations

Abstract

We outline an evolution process for tongue elements composed of poly(p-aryleneethynylene)s (PAE) and detergents, resulting in a chemical tongue (24 elements) that discerns antibiotics. Cross-breeding of this new tongue with tongue elements that consist of simple poly(p-phenyleneethynylene)s (PPE) at different pH-values leads to an enlarged sensor array, composed of 30 elements. This tongue was pruned, employing principal component analysis. We found that a filial tongue featuring three elements from each original array (i.e. a six element tongue) is superior to either of the prior tongues and the composite tongue in the discrimination of structurally different antibiotics. Such a selection process should be general and give an idea how to successfully generate powerful low-selectivity sensor elements and configure them into discriminative chemical tongues.

Graphical abstract: Fingerprinting antibiotics with PAE-based fluorescent sensor arrays

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 10 Feb 2017, accepted on 31 Mar 2017 and first published on 31 Mar 2017


Article type: Paper
DOI: 10.1039/C7PY00227K
Citation: Polym. Chem., 2017, Advance Article
  •   Request permissions

    Fingerprinting antibiotics with PAE-based fluorescent sensor arrays

    J. Han, B. Wang, M. Bender, J. Pfisterer, W. Huang, K. Seehafer, M. Yazdani, V. M. Rotello, C. M. Rotello and U. H. F. Bunz, Polym. Chem., 2017, Advance Article , DOI: 10.1039/C7PY00227K

Search articles by author