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Acid-Catalyzed Reaction of 2-Hydroxycyclobutanone with Benzylic Alcohols

Abstract

The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.

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Publication details

The article was received on 14 Oct 2017, accepted on 09 Nov 2017 and first published on 10 Nov 2017


Article type: Paper
DOI: 10.1039/C7OB02545A
Citation: Org. Biomol. Chem., 2017, Accepted Manuscript
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    Acid-Catalyzed Reaction of 2-Hydroxycyclobutanone with Benzylic Alcohols

    F. Secci, R. Guillot, D. J. Aitken, A. Frongia, M. Arca, G. Sarais, A. Luridiana and A. Martis, Org. Biomol. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7OB02545A

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