Jump to main content
Jump to site search

Issue 44, 2017
Previous Article Next Article

Chemoselective N-arylation of aminobenzamides via copper catalysed Chan–Evans–Lam reactions

Author affiliations

Abstract

Chemoselective N-arylation of unprotected aminobenzamides was achieved via Cu-catalysed Chan–Evans–Lam cross-coupling with aryl boronic acids for the first time. Simple copper catalysts enable the selective arylation of amino groups in ortho/meta/para-aminobenzamides under open-flask conditions. The reactions were scalable and compatible with a wide range of functional groups.

Graphical abstract: Chemoselective N-arylation of aminobenzamides via copper catalysed Chan–Evans–Lam reactions

Back to tab navigation

Supplementary files

Publication details

The article was received on 08 Oct 2017, accepted on 23 Oct 2017 and first published on 23 Oct 2017


Article type: Communication
DOI: 10.1039/C7OB02491F
Citation: Org. Biomol. Chem., 2017,15, 9288-9292
  •   Request permissions

    Chemoselective N-arylation of aminobenzamides via copper catalysed Chan–Evans–Lam reactions

    S. Liu, W. Zu, J. Zhang and L. Xu, Org. Biomol. Chem., 2017, 15, 9288
    DOI: 10.1039/C7OB02491F

Search articles by author

Spotlight

Advertisements