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Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase

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Abstract

Monodisperse thermoresponsive cyclodextrins appended with benzenesulfonamides were demonstrated to reversibly regulate the enzymatic activity of carbonic anhydrase, which was found to be dependent on both scaffold effect and thermoresponsiveness.

Graphical abstract: Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase

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Publication details

The article was received on 30 Aug 2017, accepted on 14 Sep 2017 and first published on 14 Sep 2017


Article type: Communication
DOI: 10.1039/C7OB02171B
Citation: Org. Biomol. Chem., 2017, Advance Article
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    Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase

    A. Qian, H. Shi, R. Zhu, J. Yan, W. Li, K. Liu and A. Zhang, Org. Biomol. Chem., 2017, Advance Article , DOI: 10.1039/C7OB02171B

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