Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA

Toshiki Chiba; Takaya Sato; Yusuke Sato; Seiichi Nishizawa

doi:10.1039/C7OB02077E

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Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA†

Toshiki Chiba,

^a Takaya Sato,

^a Yusuke Sato

^a and Seiichi Nishizawa

*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan
E-mail: nishi@m.tohoku.ac.jp
Fax: +81-22-795-6549
Tel: +81-22-795-6552

Abstract

Red-emissive fluorescent probes have been developed by integration of quinoline blue or thiazole red as the base surrogate into triplex-forming PNAs, allowing selective sensing of a sequence of double-stranded RNA.

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Article information

DOI: https://doi.org/10.1039/C7OB02077E
Article type: Communication
Submitted: 21 Aug 2017
Accepted: 06 Sep 2017
First published: 06 Sep 2017

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Org. Biomol. Chem., 2017,15, 7765-7769

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Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA

T. Chiba, T. Sato, Y. Sato and S. Nishizawa, Org. Biomol. Chem., 2017, 15, 7765 DOI: 10.1039/C7OB02077E

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Organic & Biomolecular Chemistry

Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA†

Abstract

Supplementary files

Article information

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Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA

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