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Visible light-induced C3-sulfonamidation of imidazopyridines with sulfamides

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Abstract

A visible light-induced regioselective sulfonamidation of imidazo[1,2-a]pyridines was developed using sulfamides as the nitrogen sources and aqueous NaClO solution as the oxidant under mild conditions. With the imidazo[1,2-a]pyridines bearing various substituents, the reaction proceeded smoothly to furnish the C3-sulfonamidation products in moderate to good yields. The method was also suitable for the sulfonamidation of some other imidazoheterocycles.

Graphical abstract: Visible light-induced C3-sulfonamidation of imidazopyridines with sulfamides

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Publication details

The article was received on 15 Aug 2017, accepted on 04 Sep 2017 and first published on 05 Sep 2017


Article type: Paper
DOI: 10.1039/C7OB02029E
Citation: Org. Biomol. Chem., 2017, Advance Article
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    Visible light-induced C3-sulfonamidation of imidazopyridines with sulfamides

    Y. Gao, S. Chen, W. Lu, W. Gu, P. Liu and P. Sun, Org. Biomol. Chem., 2017, Advance Article , DOI: 10.1039/C7OB02029E

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