Jump to main content
Jump to site search

Issue 30, 2017
Previous Article Next Article

tert-Butyl nitrite (TBN) as the N atom source for the synthesis of substituted cinnolines with 2-vinylanilines and a relevant mechanism was studied

Author affiliations

Abstract

A green method to synthesize cinnolines by 6π electrocyclic reaction with alkenyl amines and TBN has been developed. TBN plays a dual role both as a nitrogen atom source and an oxidant in this procedure. Relevant mechanism experiments reveal that the reaction proceeds through electrocyclic reaction and with diazo hydroxide as a key intermediate.

Graphical abstract: tert-Butyl nitrite (TBN) as the N atom source for the synthesis of substituted cinnolines with 2-vinylanilines and a relevant mechanism was studied

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Jun 2017, accepted on 13 Jul 2017 and first published on 13 Jul 2017


Article type: Communication
DOI: 10.1039/C7OB01553D
Citation: Org. Biomol. Chem., 2017,15, 6318-6322
  •   Request permissions

    tert-Butyl nitrite (TBN) as the N atom source for the synthesis of substituted cinnolines with 2-vinylanilines and a relevant mechanism was studied

    X. Pang, L. Zhao, D. Zhou, P. Y. He, Z. An, J. X. Ni and R. Yan, Org. Biomol. Chem., 2017, 15, 6318
    DOI: 10.1039/C7OB01553D

Search articles by author

Spotlight

Advertisements