Issue 38, 2017

Palladium-catalyzed oxidative coupling of arylboronic acid with isocyanide to form aromatic carboxylic acids

Abstract

A valuable palladium-catalyzed oxidative coupling of aryl- and alkenyl borides with isocyanide for the synthesis of corresponding carboxylic acids has been developed. With wide substrate scopes and good functional group tolerance, this reaction offers corresponding carboxylic acids in moderate to excellent yields.

Graphical abstract: Palladium-catalyzed oxidative coupling of arylboronic acid with isocyanide to form aromatic carboxylic acids

Supplementary files

Article information

Article type
Paper
Submitted
13 Jun 2017
Accepted
06 Sep 2017
First published
06 Sep 2017

Org. Biomol. Chem., 2017,15, 8078-8083

Palladium-catalyzed oxidative coupling of arylboronic acid with isocyanide to form aromatic carboxylic acids

Z. Chen, K. Liu, F. Zhang, Q. Yuan and Y. Zhu, Org. Biomol. Chem., 2017, 15, 8078 DOI: 10.1039/C7OB01428G

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