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The synthesis of cycloalka[b]furans via an Au(I)-catalyzed tandem reaction of 3-yne-1,2-diols

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Abstract

An Au(I)-catalyzed cyclization/1,2-rearrangement/aromatization cascade of 3-yne-1,2-diols has been successfully realized. This reaction not only provides a new and efficient strategy for the synthesis of substituted cycloalka[b]furan compounds as well as their derivatives, but might also facilitate related biological studies.

Graphical abstract: The synthesis of cycloalka[b]furans via an Au(i)-catalyzed tandem reaction of 3-yne-1,2-diols

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Publication details

The article was received on 15 May 2017, accepted on 14 Jul 2017 and first published on 14 Jul 2017


Article type: Communication
DOI: 10.1039/C7OB01179B
Citation: Org. Biomol. Chem., 2017, Advance Article
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    The synthesis of cycloalka[b]furans via an Au(I)-catalyzed tandem reaction of 3-yne-1,2-diols

    W. Liu, Z. Xu, X. Mou, B. Zhang, W. Bao, S. Wang, D. Lee, L. Lei and K. Zhang, Org. Biomol. Chem., 2017, Advance Article , DOI: 10.1039/C7OB01179B

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