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Issue 30, 2017
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19F CEST imaging probes for metal ion detection

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Abstract

For detecting metal ions with 19F chemical exchange saturation transfer magnetic resonance imaging (19F CEST MRI), a class of novel fluorinated chelators with diverse fluorine contents and chelation properties were conveniently synthesized on gram scales. Among them, a DTPA-derived chelator with high sensitivity and selectivity was identified as a novel 19F CEST imaging probe for simultaneously detecting multiple metal ions.

Graphical abstract: 19F CEST imaging probes for metal ion detection

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Publication details

The article was received on 03 May 2017, accepted on 14 Jul 2017 and first published on 14 Jul 2017


Article type: Paper
DOI: 10.1039/C7OB01068K
Citation: Org. Biomol. Chem., 2017,15, 6441-6446
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    19F CEST imaging probes for metal ion detection

    Q. Peng, Y. Yuan, H. Zhang, S. Bo, Y. Li, S. Chen, Z. Yang, X. Zhou and Z. Jiang, Org. Biomol. Chem., 2017, 15, 6441
    DOI: 10.1039/C7OB01068K

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