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19F CEST imaging probes for metal ions detection

Abstract

To detecting metal ions with 19F chemical exchange saturation transfer magnetic resonance imaging (19F CEST MRI), a class of novel fluorinated chelators with diverse fluorine contents and chelation properties were conveniently synthesized on gram scales. From them, a DTPA derived chelator with high sensitivity and selectivity was identified as a novel 19F CEST imaging probe for simutaneously detecting multiple metal ions.

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Publication details

The article was received on 03 May 2017, accepted on 14 Jul 2017 and first published on 14 Jul 2017


Article type: Paper
DOI: 10.1039/C7OB01068K
Citation: Org. Biomol. Chem., 2017, Accepted Manuscript
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    19F CEST imaging probes for metal ions detection

    Q. Peng, Y. Yuan, H. Zhang, S. Bo, Y. Li, S. Chen, Z. Yang, X. Zhou and Z. Jiang, Org. Biomol. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7OB01068K

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