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Push–pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging

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Abstract

A series of push–pull type meso-ester substituted BODIPY dyes 1–4 with intense near-infrared absorption, largely enhanced photoacoustic (PA) activity and excellent photo-stability were synthesized. The impact of the electronic structure on the PA activity was also discussed. Moreover, the in vitro and in vivo PA imaging were investigated, which suggested a passive targeting capacity in the tumor site.

Graphical abstract: Push–pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging

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Publication details

The article was received on 20 Apr 2017, accepted on 08 May 2017 and first published on 08 May 2017


Article type: Communication
DOI: 10.1039/C7OB00965H
Citation: Org. Biomol. Chem., 2017, Advance Article
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    Push–pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging

    Y. Ni, R. K. Kannadorai, S. W.-K. Yu, Y. Chang and J. Wu, Org. Biomol. Chem., 2017, Advance Article , DOI: 10.1039/C7OB00965H

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