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Issue 22, 2017
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Lipoic acid based core cross-linked micelles for multivalent platforms: design, synthesis and application in bio-imaging and drug delivery

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Abstract

Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water. The presence of numerous disulfides accumulated in the core makes the micelles readily cross-linked to achieve the establishment of core cross-linked micelles (CCMs). Thanks to the inherent biocompatibility, the resulting lipoic acid based CCMs (LA-CCMs) are good multivalent platforms for biomedical applications.

Graphical abstract: Lipoic acid based core cross-linked micelles for multivalent platforms: design, synthesis and application in bio-imaging and drug delivery

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Publication details

The article was received on 14 Apr 2017, accepted on 15 May 2017 and first published on 15 May 2017


Article type: Communication
DOI: 10.1039/C7OB00927E
Citation: Org. Biomol. Chem., 2017,15, 4798-4802
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    Lipoic acid based core cross-linked micelles for multivalent platforms: design, synthesis and application in bio-imaging and drug delivery

    J. Huang, F. Wu, Y. Yu, H. Huang, S. Zhang and J. You, Org. Biomol. Chem., 2017, 15, 4798
    DOI: 10.1039/C7OB00927E

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