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Lipoic Acid Based Core Cross-linked Micelles for Multivalent Platform: Design, Synthesis and Application in Bio-imaging and Drug Delivery

Abstract

Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water. The presence of numerous disulfides accumulated in the core makes the micelles readily be cross-linked to achieve the establishment of core cross-linked micelles (CCMs). Thanks to the inherent biocompatibility, the resulting lipoic acid based CCMs (LA-CCMs) are good multivalent platforms for biomedical application.

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Publication details

The article was received on 14 Apr 2017, accepted on 15 May 2017 and first published on 15 May 2017


Article type: Communication
DOI: 10.1039/C7OB00927E
Citation: Org. Biomol. Chem., 2017, Accepted Manuscript
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    Lipoic Acid Based Core Cross-linked Micelles for Multivalent Platform: Design, Synthesis and Application in Bio-imaging and Drug Delivery

    J. Huang, F. Wu, Y. Yu, H. Huang, S. Zhang and J. You, Org. Biomol. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7OB00927E

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