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Issue 23, 2017
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Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

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Abstract

We developed a novel phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides (p-QMs). This reaction provided a promising method for the synthesis of triarylmethanes, which widely exist in natural products and in molecules which have been shown to have biological and pharmacological activity.

Graphical abstract: Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

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Publication details

The article was received on 12 Apr 2017, accepted on 29 Apr 2017 and first published on 02 May 2017


Article type: Communication
DOI: 10.1039/C7OB00911A
Citation: Org. Biomol. Chem., 2017,15, 4941-4945
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    Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

    T. Zhou, S. Li, B. Huang, C. Li, Y. Zhao, J. Chen, A. Chen, Y. Xiao, L. Liu and J. Zhang, Org. Biomol. Chem., 2017, 15, 4941
    DOI: 10.1039/C7OB00911A

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