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Metal-free I2O5-mediated direct construction of sulfonamides from thiols and amines

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Abstract

A simple and convenient method has been developed for the construction of sulfonamides via I2O5-mediated sulfonylation of amines with arylthiols. The present protocol provides an attractive approach to sulfonamides in moderate to good yields from readily accessible and easy to handle starting materials under mild and metal-free conditions.

Graphical abstract: Metal-free I2O5-mediated direct construction of sulfonamides from thiols and amines

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Publication details

The article was received on 17 Mar 2017, accepted on 10 May 2017 and first published on 12 May 2017


Article type: Communication
DOI: 10.1039/C7OB00668C
Citation: Org. Biomol. Chem., 2017, Advance Article
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    Metal-free I2O5-mediated direct construction of sulfonamides from thiols and amines

    M. Zhu, W. Wei, D. Yang, H. Cui, L. Wang, G. Meng and H. Wang, Org. Biomol. Chem., 2017, Advance Article , DOI: 10.1039/C7OB00668C

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