Jump to main content
Jump to site search

Issue 12, 2017
Previous Article Next Article

Base-mediated insertion reaction of alkynes into carbon–carbon σ-bonds of ethanones: synthesis of hydroxydienone and chromone derivatives

Author affiliations

Abstract

Transition-metal free insertions of alkynes into carbon–carbon σ-bonds of ethanones have been reported. These tandem reactions offer an efficient synthesis of hydroxydienones and multi-substituted chromones. This is the first example of base-promoted insertion reactions of isolated carbon–carbon triple bonds into carbon–carbon σ-bonds with active methylene compounds bearing only one electron-withdrawing group.

Graphical abstract: Base-mediated insertion reaction of alkynes into carbon–carbon σ-bonds of ethanones: synthesis of hydroxydienone and chromone derivatives

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Feb 2017, accepted on 28 Feb 2017 and first published on 07 Mar 2017


Article type: Communication
DOI: 10.1039/C7OB00476A
Citation: Org. Biomol. Chem., 2017,15, 2497-2500
  •   Request permissions

    Base-mediated insertion reaction of alkynes into carbon–carbon σ-bonds of ethanones: synthesis of hydroxydienone and chromone derivatives

    F. Zhang, Q. Yao, Y. Yuan, M. Xu, L. Kong and Y. Li, Org. Biomol. Chem., 2017, 15, 2497
    DOI: 10.1039/C7OB00476A

Search articles by author

Spotlight

Advertisements