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Issue 16, 2017
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Post-synthetic modification of tryptophan containing peptides via NIS mediation

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Abstract

A new efficient method was developed to provide modified tryptophan peptides through NIS (N-iodosuccinimide) mediated N2-selective coupling of a Trp unit with 1,2,3-triazoles, of which, the preliminary spectral properties were also studied.

Graphical abstract: Post-synthetic modification of tryptophan containing peptides via NIS mediation

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Publication details

The article was received on 11 Feb 2017, accepted on 20 Mar 2017 and first published on 20 Mar 2017


Article type: Communication
DOI: 10.1039/C7OB00329C
Citation: Org. Biomol. Chem., 2017,15, 3396-3400
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    Post-synthetic modification of tryptophan containing peptides via NIS mediation

    C. Gu, Q. Bi, C. Gao, J. Wen, Z. Zhao and Z. Chen, Org. Biomol. Chem., 2017, 15, 3396
    DOI: 10.1039/C7OB00329C

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