Jump to main content
Jump to site search


Azobenzene-Benzoylphenylureas as Photoswitchable Chitin Synthesis Inhibitors

Abstract

Benzoylphenylureas (BPUs) are used as synthetic insect growth regulators for inhibiting the chitin synthesis. Merging insecticidal BPUs with photoswitchable azobenzene generated the photoresponsive chitin synthesis inhibitors. One prepared azobenzene-benzoylphenylurea can be activated upon irradiation of UV light, which shows 6-fold and 2-fold activity difference to armyworm (Mythimna separate) and German cockroach (Blattlla germanica) sulfonylurea receptor, respectively. This is the first example of photoswitchable BPU insecticide. The generation of such photoresponsive BPU insecticide allows for modulating the insecticidal activity by light and may facilitate the spatiotemporal control over the sulfonylurea receptor and the mechanism study of this kind of insecticide.

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 27 Dec 2016, accepted on 14 Mar 2017, published on 17 Mar 2017 and first published online on 17 Mar 2017


Article type: Paper
DOI: 10.1039/C6OB02813F
Citation: Org. Biomol. Chem., 2017, Accepted Manuscript
  •   Request permissions

    Azobenzene-Benzoylphenylureas as Photoswitchable Chitin Synthesis Inhibitors

    X. Tian, C. Zhang, Q. Xu, Z. Li and X. Shao, Org. Biomol. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C6OB02813F

Search articles by author