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Issue 3, 2017
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C–H functionalisation of cycloalkanes

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Abstract

Among organic compounds hydrocarbons are inexpensive and possibly the most abundant among natural resources. Developing strategies for selective functionalisation of inert hydrocarbon C–H bonds is one of the most ideal synthetic paths that a synthetic chemist could think of. This critical review focuses on the recent development of various directed and non-directed cycloalkylations leading to the formation of carbon–carbon (C–C) and carbon–heteroatom (C–X) bonds. Apart from various transition metal catalysed cycloalkylations, this review also covers various metal-free cycloalkylation processes.

Graphical abstract: C–H functionalisation of cycloalkanes

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Publication details

The article was received on 07 Sep 2016, accepted on 25 Nov 2016 and first published on 25 Nov 2016


Article type: Review Article
DOI: 10.1039/C6OB01975G
Citation: Org. Biomol. Chem., 2017,15, 505-530
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    C–H functionalisation of cycloalkanes

    A. Banerjee, S. Sarkar and B. K. Patel, Org. Biomol. Chem., 2017, 15, 505
    DOI: 10.1039/C6OB01975G

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