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Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

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Abstract

Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (AbEGFR) antibody (N-GQD-PEI-PSS-AbEGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.

Graphical abstract: Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

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Publication details

The article was received on 13 Sep 2017, accepted on 16 Nov 2017 and first published on 17 Nov 2017


Article type: Communication
DOI: 10.1039/C7NR06836K
Citation: Nanoscale, 2018, Advance Article
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    Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

    P. Wu, J. Wang, W. Wang, C. Chang, C. Huang, K. Yang, J. Chang, C. L. Hsu, S. Chen, T. Chou and W. Kuo, Nanoscale, 2018, Advance Article , DOI: 10.1039/C7NR06836K

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