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Post-targeting strategy for ready-to-use targeted nanodelivery post cargo loading

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Abstract

Based on boronate formation, this study reports a post-targeting methodology capable of readily installing versatile targeting modules onto a cargo-loaded nanoplatform in aqueous mediums. This permits the targeted nanodelivery of broad-spectrum therapeutics (drug/gene) in a ready-to-use manner while overcoming the PEGylation-dilemma that frequently occurs in conventional targeting approaches.

Graphical abstract: Post-targeting strategy for ready-to-use targeted nanodelivery post cargo loading

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Publication details

The article was received on 16 Aug 2017, accepted on 18 Nov 2017 and first published on 21 Nov 2017


Article type: Communication
DOI: 10.1039/C7NR06080G
Citation: Nanoscale, 2017, Advance Article
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    Post-targeting strategy for ready-to-use targeted nanodelivery post cargo loading

    J. Y. Zhu, J. J. Hu, M. K. Zhang, W. Y. Yu, D. W. Zheng, X. Q. Wang, J. Feng and X. Z. Zhang, Nanoscale, 2017, Advance Article , DOI: 10.1039/C7NR06080G

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