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Issue 43, 2017
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Nanofabrication of mechano-bactericidal surfaces

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The search for alternatives to the standard methods of preventing bacterial adhesion and biofilm formation on biotic and abiotic surfaces alike has led to the use of biomimetics to reinvent through nanofabrication methods, surfaces, whereby the nanostructured topography is directly responsible for bacterial inactivation through physico-mechanical means. Plant leaves, insect wings, and animal skin have been used to inspire the fabrication of synthetic high-aspect-ratio nanopillared surfaces, which can resist bacterial colonisation. The adaptation of bacteria to survive in the presence of antibiotics and their ability to form biofilms on conventional antibacterial surfaces has led to an increase in persistent infections caused by resistant strains of bacteria. This presents a worldwide health epidemic that can only be mitigated through the search for a new generation of biomaterials.

Graphical abstract: Nanofabrication of mechano-bactericidal surfaces

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The article was received on 09 Aug 2017, accepted on 12 Oct 2017 and first published on 13 Oct 2017

Article type: Review Article
DOI: 10.1039/C7NR05881K
Citation: Nanoscale, 2017,9, 16564-16585
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    Nanofabrication of mechano-bactericidal surfaces

    D. P. Linklater, S. Juodkazis and E. P. Ivanova, Nanoscale, 2017, 9, 16564
    DOI: 10.1039/C7NR05881K

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