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Porphyrin- or phthalocyanine- bridged silsesquioxane theranostic nanoparticles for two-photon imaging, photodynamic therapy or photoacoustic imaging

Abstract

Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Their endocytosis in MCF-7 cancer cells was shown with two-photon excited fluorescence imaging (TPEF) imaging. With two-photon excited photodynamic therapy (TPE-PDT) BSPOR was more phototoxic than BSPHT, which in contrast displayed a very high signal for photoacoustic imaging in mice.

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Publication details

The article was received on 28 Jun 2017, accepted on 01 Oct 2017 and first published on 03 Oct 2017


Article type: Communication
DOI: 10.1039/C7NR04677D
Citation: Nanoscale, 2017, Accepted Manuscript
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    Porphyrin- or phthalocyanine- bridged silsesquioxane theranostic nanoparticles for two-photon imaging, photodynamic therapy or photoacoustic imaging

    C. Mauriello-Jimenez, M. Henry, D. Aggad, L. Raehm, C. Charnay, X. Cattoen, M. Wong Chi Man, S. Alpugan, V. Ahsen, D. K. Tarakcı, P. Maillard, M. Maynadier, M. Garcia, F. Dumoulin, M. Gary-Bobo, J. Coll, V. Josserand and J. Durand, Nanoscale, 2017, Accepted Manuscript , DOI: 10.1039/C7NR04677D

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