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Silicon-Based Nanotheranostics

Abstract

With the rapid expansion of nanoscience and nanotechnology in interdisciplinary fields, multifunctional nanomaterials attracted particular attention. Recent advances in nanotherapeutics for cancer applications provided diverse groups of synthetic particles with defined cellular and biological functions. The advance of nanotechnology significantly increased the number of possibilities for construction of diverse biological tools. Such materials are destined to become of great importance because of the opportunity to combine the biotechnological potential of nanoparticles together with the recognition, sensitivity, and modulation of cellular pathways or genes when applied to living organisms. In this minireview three main types of Si-based nanomaterials are highlighted in the area of their application for therapy and imaging: porous silicon nanoparticles (pSiNPs), mesoporous silica nanoparticles (MSNs), focusing on their nanoconstructs containing coordination compounds, and periodic mesoporous silica nanoparticles (PMONPs). Moreover, a critical discussion of the research efforts in construction of nanotheranostics is presented.

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Publication details

The article was received on 20 Jun 2017, accepted on 10 Aug 2017 and first published on 11 Aug 2017


Article type: Minireview
DOI: 10.1039/C7NR04445C
Citation: Nanoscale, 2017, Accepted Manuscript
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    Silicon-Based Nanotheranostics

    N. Knezevic and G. Kaluđerović, Nanoscale, 2017, Accepted Manuscript , DOI: 10.1039/C7NR04445C

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